Introduction
Thymesia’s plague weapons are central to mastering combat. With 21 unique options, choosing the right weapons to upgrade can make the difference between a smooth journey and a grueling one. In this guide, we’ll cover the best plague weapons in Thymesia, why they stand out, and which combos can maximize your damage output.

Best Early-Game Plague Weapons

• Halberd: A versatile weapon that knocks enemies down, providing an opening for follow-up attacks. The third jab can break super armor, making it ideal for dealing with tougher foes.
  • Recommended Upgrade Path: Focus on the offensive buff and extending its combo for maximum effectiveness.
• Bow: Offers 300% attack damage and 600% wound damage, with the ability to interrupt critical attacks. Its range and damage make it invaluable against both bosses and regular enemies.
  • Strength Scaling: Increases casting speed and applies a bleed effect with Plague investment.
• Scythe: A must-have for early healing. Restores health on hit and scales with Plague, making it a reliable option for sustained fights.

Mid-Game Must-Haves

• Whip: Deals 400% attack and wound damage with a short cooldown. It stacks offensive buffs quickly and is effective against heavily armored enemies.
• Greatsword: Exceptional for its ability to knock down bosses and high-damage output (350% attack and wound damage). Allows for multiple follow-up hits while enemies are down.
• Twin Swords: Ideal for stacking wound damage rapidly. Scales with both Strength and Plague, making it perfect for melting boss health bars.

Best Boss Weapons

• Mutated Tentacles: Long-range and stacks offensive buffs with each cast. Great for safely dealing damage from afar.
• Giant Sword: The hardest-hitting plague weapon with over 1000% damage when fully upgraded. Best used with high Vitality for reduced damage during casts.
• Javelin: A long-range option that deals 240% attack damage plus 300% claw damage through its explosive effect. Perfect for finishing off enemies safely.

Ultimate Combo: Bow + Javelin
This combo allows you to deal massive wound damage from a distance, making it effective for bosses that keep their distance or are difficult to approach.

• Bow: For initiating with high burst damage.
• Javelin: To finish enemies off without needing to close the gap.

Conclusion
Choosing the right plague weapons and combos in Thymesia is crucial for progressing smoothly. Focus on unlocking and upgrading these top picks based on your playstyle—whether you prefer aggressive melee or tactical ranged combat. Master these weapons, and you’ll find yourself slicing through enemies with ease. Best of luck, plague doctor!