In Atelier Ryza 3, few weapons can match the sheer destructive power of the Mistel Cane when it’s optimized correctly. This guide will walk you through how to craft the most overpowered weapon in the game—capable of dealing over a million damage on the hardest difficulty without any buffs or debuffs. With this setup, you’ll be wiping out enemies with ease, even on Charismatic difficulty.

Why the Mistel Cane?

Unlike Ryza’s final-tier weapon, the Mistel Cane offers unparalleled customization and damage potential. The recipe for this weapon can be obtained either from a rare supply point requiring a super rare key or from a standard NPC quest, though it’s generally acquired later in the game.

The Mistel Cane’s true power lies in its ability to stack elemental damage boosts alongside devastating traits, making it the ideal weapon for maximizing the damage of core items like the Zwei Resonance.

Step 1: Preparing the Materials

Key Ingredients

• Grand Organ: The best ingot for maximizing stats.
• Water Seeds: Must have traits like Risk Boost Fire and Risk Boost Ice.
• Philosopher’s Stones: Used for spreading and maximizing element effects.
• Inverted Scale: For changing effects via Link Morph.

It’s crucial to gather water seeds with the right traits—Risk Boost Fire and Risk Boost Ice—as these provide a 50% boost to fire and ice damage, respectively.

Step 2: Crafting the Mistel Cane

Key Traits to Apply

• Risk Boost Fire: +50% fire damage.
• Risk Boost Ice: +50% ice damage.
• Lone Wolf Spirit: Optional for AP generation or substitute with Stat Charge++.

Super Trait

• Rook Sasha: Greatly increases damage but reduces all resistances, turning Ryza into a glass cannon.

By stacking Risk Boost Fire and Ice, you can achieve a 100% damage boost, effectively doubling your output for elemental attacks.

Synthesis Tips

• Use Secret Keys: Apply keys with Quantity Up to maximize ingot usage.
• Philosopher’s Stones: Use these to unlock every potential ability on the weapon.
• Link Morph: Replace useless effects with Item Boost for a 10% increase in item damage.

Step 3: Reinforcing the Mistel Cane

To push the Mistel Cane to its absolute limits, reinforcing it is essential.

Recommended Effects

• Four Color Fever X: Increases fire, ice, bolt, and air damage.
• Unchanging Effect IV: Boosts core item damage significantly.

Stat Prioritization

Since the Mistel Cane loses attack when reinforced, focus on boosting speed instead. Use Rock Salo to add extra speed for quicker item usage.

Step 4: Unleashing the Damage

With this setup, the Zwei Resonance becomes an absolute monster, capable of dealing over 1 million damage. Here’s a breakdown:

• Without Buffs: Can hit for 223,000 to 445,000 per hit.
• Fully Optimized: Potential to reach 1 million damage with accessory optimization.

Even against enemies with resistances, the Mistel Cane allows you to punch through with sheer elemental force.

Conclusion

The Mistel Cane isn’t just a weapon; it’s a game-changer. With the right traits, effects, and reinforcement strategy, you’ll turn Ryza into an unstoppable force. Follow this guide to maximize your damage output and trivialize even the toughest encounters in Atelier Ryza 3.

Happy crafting, and may your enemies turn to dust!