High on Life takes the concept of weaponry to a whole new level with its roster of talking guns—each with its own personality, abilities, and hilarious dialogue. These Gatlians aren’t just tools of destruction; they’re full-fledged characters that interact with you, each other, and the world around them. Whether you’re slicing through enemies with Knifey or unleashing powerful explosive attacks with Creature, each weapon provides a unique experience that enhances both combat and storytelling. Let’s break down all the crazy weapons you’ll use in High on Life and how to make the most of them.

Kenny – Your First and Most Talkative Companion

Kenny is the first Gatlian you encounter, and he quickly becomes your main guide through the absurd world of High on Life. As a mid-range pistol, Kenny offers reliable firepower with his standard shots, but his true strength lies in his Glob Shot, which launches enemies into the air, allowing you to juggle them for extra damage. His dialogue is non-stop, ranging from panicked instructions to sarcastic commentary, making him both a useful and entertaining companion.

Best Use:

• Use Glob Shot to launch enemies and combo with additional shots.
• Great for crowd control and setting up aerial damage chains.
• Provides key narrative interactions and expository dialogue.

Knifey – The Most Psychotic Blade in the Galaxy

Knifey is exactly what he sounds like: a bloodthirsty, overly excited knife that just wants to stab everything in sight. He doesn’t just function as a melee weapon—he’s also essential for tethering and swinging across gaps, making him a necessary tool for platforming sections. His disturbing obsession with stabbing adds a twisted sense of humor to the gameplay.

Best Use:

• Close-range instant kills on weaker enemies.
• Allows you to tether and swing across gaps.
• Can be used to execute finishing moves on stunned foes.
• A mandatory tool for opening Luglox chests throughout the game.

Gus – The Shotgun With Attitude

After defeating Krubus, you unlock Gus, a shotgun-style Gatlian with serious stopping power. His disc-shot ability lets you launch enemies into walls or knock them into environmental hazards. He also provides suction power, pulling enemies in for close-range devastation. Gus is great for players who like to get up close and personal in combat.

Best Use:

• Close-range combat with devastating shotgun blasts.
• Use his suction ability to pull in enemies before finishing them off.
• Fire discs at walls to create temporary platforms for traversal.
• Key weapon for handling tight combat situations with multiple enemies.

Sweezy – The Time-Manipulating Chaos Dealer

Sweezy is the ultimate weapon for strategic combat. Her primary fire is a burst shot, but her time-bubble ability is where she shines. By slowing down enemies and projectiles, she gives you full control of the battlefield, making her one of the most versatile weapons in the game. She’s also great for solving environmental puzzles that require slowed-down movement.

Best Use:

• Time Bubble can freeze enemies, making them easy to pick off.
• Great against fast-moving enemies or bosses with high-speed attacks.
• Synergizes well with other weapons—freeze enemies and swap to another gun for a finishing blow.
• Can slow down fans or fast-moving obstacles in the environment.

Creature – The Weirdest Weapon in the Game

Creature is a bizarre and unsettling weapon that spawns tiny, living creatures that attack enemies for you. These little guys latch onto enemies and explode, causing massive damage. He also has the ability to mind-control enemies, forcing them to fight alongside you for a short period. While his damage output isn’t the highest, his utility makes him incredibly useful in tricky combat situations.

Best Use:

• Spawn creatures to attack enemies while you stay at a distance.
• Use his mind-control ability to turn enemies against each other.
• Great for setting up distractions and overwhelming foes with sheer numbers.
• Can be used to disable certain security systems by sending creatures through vents.

Let’s Do It – The Ultimate Powerhouse

After much of the game builds up to his revival, Let’s Do It returns as a devastatingly powerful weapon with unmatched firepower. He’s essentially a gatling gun-style super weapon, capable of tearing through hordes of enemies with ease. The only downside? His vocabulary is extremely limited—he can only say his name.

Best Use:

• Best for endgame combat, dealing massive damage in a short period.
• Perfect for taking down bosses and heavily armored enemies.
• Has an extremely high rate of fire, making it ideal for chaotic battles.
• The emotional payoff of using him adds a unique layer to the experience.

Making the Most of Your Arsenal

To fully maximize your effectiveness in High on Life, you’ll want to switch between weapons frequently and take advantage of their unique abilities. Here are a few key strategies:

• Combo Your Abilities – Use Kenny’s Glob Shot to launch enemies, then swap to Gus for a shotgun blast.
• Time Your Bubbles – Slow down enemies with Sweezy before launching high-damage attacks.
• Keep Moving – The game rewards mobility, so use Knifey’s tether ability to stay agile.
• Experiment with Mind Control – Creature’s minions can be game-changers in larger fights.
• Upgrade Your Weapons – Visit the pawn shop frequently to get mods that enhance their abilities.

Conclusion – A Cast of Weapons Unlike Any Other

High on Life turns weapons into full-fledged characters, making them more than just tools of destruction. Each Gatlian has a personality, a purpose, and a unique set of skills that makes gameplay varied and engaging. Whether you prefer the controlled precision of Kenny, the destructive blasts of Gus, or the sheer insanity of Creature, there’s a weapon for every playstyle.

No matter how you choose to play, one thing is certain—these weapons will talk your ear off while helping you blast your way through the galaxy. Now, go out there, pick your favorite talking gun, and bring down the G3 cartel in the most chaotic way possible!