In Mass Effect: Andromeda, biotic abilities are some of the most visually impressive and tactically flexible powers available. Whether you’re a full-on caster or prefer a hybrid combat style, mastering the biotic tree can open up some devastating combos and defensive strategies. This guide provides a deep dive into every active and passive biotic skill—how they work, how they synergize, and which upgrades make them shine on higher difficulties like Insanity.


Pull & Throw – The Classic Combo Reimagined

Pull acts as both a crowd control tool and a combo primer. You can lift enemies (or even explosive barrels) into the air and then combine it with Throw to toss them into enemies or the environment. However, Pull suffers on higher difficulties, especially against shielded or armored foes who can resist the levitation effect. Its utility is limited unless you’re using it for environmental interactions or chaining combos.

Throw, on the other hand, is much more useful. It’s a combo detonator with a low cooldown, enemy tracking, and solid force, making it a strong choice even on Insanity. You can spec it to fire two projectiles and use it effectively behind cover, especially when detonating large crowd-control abilities like Singularity. On its own, its damage won’t carry you, but as a reliable combo finisher, it has excellent synergy potential.


Charge – High Risk, High Reward

Charge is arguably the best of the biotic abilities in terms of sheer utility. It delivers massive shields, invincibility frames during the dash, and solid burst damage. With the right upgrades—especially Rank 4’s damage boost and Rank 6’s Bastion—you can restore 100% of your shields on impact and receive up to 35% bonus damage. It becomes a core part of both offensive and defensive rotations and excels on Insanity for its survivability and burst potential. Charge remains a staple from previous Mass Effect entries for good reason.


Nova – Stylish but Situational

Nova is flashy but suffers from mobility limitations during casting and a full 100% shield cost, which makes spamming it unwise. That said, with the Anti-Shields upgrade and Seismic Nova (Rank 6), it becomes a devastating tool against shielded enemies. When paired with Charge or used in tight spaces, Nova can deliver serious AoE devastation. It can also be turned into a combo primer, making it a strategic part of multi-skill builds.


Shockwave – Flexible and Underrated

Shockwave is a versatile power that can serve as both a combo detonator and primer with the Lifting Shockwave upgrade. It has decent damage and can be specced for range or cooldown reduction. While it’s not great against armor, its ability to detonate and re-prime enemies in a chain makes it ideal for crowd control and combo spam. It’s particularly fun when enhanced with fusion mods or rapid-cast builds.


Annihilation – Passive Carnage

This toggleable AoE field shines in sustained fights. With a large base radius that can be expanded further, Annihilationdamages enemies over time and synergizes incredibly well with other biotic effects. With Damage Attraction (Rank 5), enemies take 20% more damage from all sources. Draining Field (Rank 6) restores 30% of your shields per kill, making this one of the best defensive-support skills available. Used properly, it turns you into a walking hazard zone, especially when combined with fast kills and radius expansions.


Backlash – The Reactive Barrier

Backlash is like Barricade with a biotic twist. It blocks incoming projectiles and can reflect them with the right spec. While it doesn’t allow shooting while active, you can move and absorb massive damage, especially with the Reflectionperk. Combined with Damage Aftermath at Rank 6, it transforms into a powerful defensive-offensive blend that boosts your output after a successful deflection. Ideal for a space knight-style tank build.


Singularity – Classic Crowd Control

Singularity continues its legacy as a strong AoE crowd control. With Radius and Recharge Speed upgrades, it becomes a spammable vortex that disables groups and primes them for detonations. Add Exploding Singularity (Rank 6) to cause chain reactions with stunning visual and combat results. It’s a core part of any full caster build and works especially well with Throw, Lance, or Shockwave as follow-ups.


Lance – Fast, Direct, Effective

Lance is a ranged, fast-casting biotic projectile with solid damage and utility. It excels as a combo detonator, and with Anti-Shields, it becomes great for burning down defensive enemies. Although it consumes 45% shield by default, this can be reduced with passive upgrades. Shield Powered at Rank 6 allows repeated use without constant drain, giving you sustained burst potential. It lacks tracking, so it’s best against larger targets or clustered enemies.


Barrier – Always Worth It

Barrier is a passive that provides excellent survivability across all builds. Biotic Link (Rank 5) increases your max shields based on the number of enemies affected by biotic abilities—perfect for Annihilation or Singularity builds. Saving Barrier(Rank 6) offers emergency shield restoration every 10 seconds, often saving you from death in chaotic fights. Even non-biotic builds benefit from Barrier’s scaling.


Offensive Biotics – Boost Your Power

This passive tree improves raw biotic output. Amplitude increases overall power damage, Exploitation applies a 20% defense debuff on enemies hit by biotics, and Biotic Expert or Biotic Warrior (depending on your loadout) offers either pure power scaling or weapon synergy. A must-have for full Adept profiles or hybrid power-melee playstyles.


Containment – Radius and Duration Mastery

Though often overlooked, Containment enhances AoE potential for skills like Singularity and Annihilation. Combo Detonator vs. Shields (Rank 5) boosts your power against shielded enemies—crucial on higher difficulties. At Rank 6, Event Horizon greatly increases AoE radius and force, while Manifold Duration boosts effect durations. Pick based on your combo goals or crowd control needs.


Final Thoughts

Biotic abilities in Mass Effect: Andromeda range from flashy utility skills to heavy-hitting combo components. The most effective builds mix powers like ChargeAnnihilation, and Throw for relentless offensive pressure and battlefield control. Back these with smart passive investments in BarrierOffensive Biotics, and Containment, and you’ll have a build that’s both stylish and brutally efficient—even on Insanity.

If you missed earlier breakdowns or guides, be sure to check those out—and stay tuned for more deep dives coming soon.


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